The StreptaClick® Technology
- multiplex with biotinylated antibodies

The patented StreptaClick® technology provides monovalent binding of streptavidin to biotinylated antibodies. StreptaClick® is a modified form of tetrameric streptavidin with conserved high binding affinity for biotin. Its monovalent binding property prevents antibody aggregation, which allows antibody pre-labeling in solution and multiplexing. StreptaClick® can be linked to any biotinylated antibody in a 5-minute mixing reaction, in any volume and without washing steps. Our product portfolio includes StreptaClick® labelled with fluorochromes, enzymes, and reactive groups for click chemistry.

SpectraSplit®7 – Hepta-band optical filter sets for microscopes and scanners

Specific separation of 7 fluorescent colors in a multi-stained tissue section has never been easier. The patented SpectraSplit®7 filter sets generate clean, sharp images without the need for spectral unmixing, making it suitable for any downstream application. Simply select among the most popular fluorochromes for each color channel and image without bleed-through.

SpectraSplit®7 was initially developed in 2014. Over the years the hepta-band filter sets have been fine-tuned based on customer feedback to not only fit a wide range of fluorochromes, but also different staining techniques, including Tyramide Signal Amplification and DNA-based multiplexing.

SpectraSplit®7 is compatible with  light sources from CoolLED (pE-800 SB), Lumencor (SPECTRA X light engine) and Excelitas (NOVEM-S).

Introducing StreptaClick® Precision

A novel version of StreptaClick® developed for site-specific conjugation via click chemistry and enhanced monovalent binding to biotinylated proteins.

StreptaClick® Precision has a unique design with maximum separation of the single reactive site for conjugation (azide/DBCO) and the site for biotin binding. This makes StreptaClick® Precision ideal for attachment of bulky molecules such as DNA oligos and LNPs.

StreptaClick® Precision is the ultimate choice for developing flexible, multiplex immunoassays with high precision.

Perfect for oligonucleotides and lipid nanoparticles

BiotinPure™ Antibody Biotinylation Kit

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The BiotinPure™ Antibody Biotinylation Kit is a complete kit for easy biotinylation of antibodies at room temperature within 1 hour. The kit uses amine/ester chemistry to attach 2-3 biotins per antibody and includes a purification wash step that removes unreacted free biotin from the final biotinylated antibody solution. The antibodies to be biotinylated should be free from other proteins, such as BSA. The BiotinPure™ Antibody Biotinylation Kit is designed for use with StreptaClick® reagents. The biotinylated antibodies may also be used for other applications. Cat. no. 9000051-1 Order or request further information

Request a quote or order

Request a quote or order with payment by invoice by sending us an email via the button above. When ordering, please include information on the products you wish to order, organization, VAT number (only EU countries), delivery address, and invoice address. Please also state contact person and phone number for delivery by courier. We ship globally - a shipping cost of €50 is added to countries within the EU and €80 to all other countries. Upon request we can also charge in $USD for payments by invoice.

Webshop

Orders can also be placed through our webshop via the form below.  Once a product has been added a popup will appear with the choice of proceeding to checkout or adding additional products. The shopping cart icon at the top right corner also takes you to checkout. At checkout you will have the choice of secure payment by credit card via Stripe, Apple Pay, Google Pay or invoice. Shipping charges are added automatically. NB: VAT is not added to the final cost under Article 138 VAT directive (other EU countries) and 146 VAT directive (export to non-EU countries). Select your BiotinPure™ Kit:
Select options This product has multiple variants. The options may be chosen on the product page

SpectraSplit® 7

SpectraSplit® 7 are patented filter sets that empower fluorescence microscopes with seven color channels.  The channels are distributed over four filter sets and specifically separate the most commonly used fluorochromes in immunofluorescence (see table below). Hence, you can immunostain tissues with up to seven fluorochromes and still visualize each fluorochrome in the sample with SpectraSplit® 7 without bleedthrough. No additional software and no computational spectral unmixing are required. SpectraSplit® 7 can easily be installed in both standard and scanning fluorescence microscopes, and can be run with different popular light sources. See the description below for more information. Cat no. 7001991-1 Request a quote or information

Request a quote or order

Request a quote or order with payment by invoice by sending us an email via the button above. When ordering, please include information on the products you wish to order, organization, VAT number (only EU countries), delivery address, and invoice address. Please also state contact person and phone number for delivery by courier. We ship globally – a shipping cost of €50 is added to countries within the EU and €80 to all other countries. We can also charge in $USD. NB: VAT is not added to the final cost under Article 138 VAT directive (other EU countries) and 146 VAT directive (export to non-EU countries).

StreptaClick® Color

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StreptaClick® Color is a modified streptavidin that labels antibodies with fluorochromes, mimicking directly conjugated antibodies as we have removed the issue of antibody aggregation through monovalent binding. StreptaClick® Color provides a rapid, robust, and flexible method for attaching fluorochromes to biotinylated antibodies. Once labeled with StreptaClick®, the antibody is stable and can be used in the same manner as antibodies that are directly conjugated with fluorochromes. The labeling reaction is highly efficient and can be carried out at any volume, concentration, or buffer.
  • The StreptaClick® Color 2-plex Kit contains: StreptaClick® Color 488 and StreptaClick® Color 647. Suitable for multiplex immunohistochemistry (IHC) and Flow Cytometry. (Cat. no. 50021-1)
  • The StreptaClick® Color 4-plex Kit contains: StreptaClick® Color 488, StreptaClick® Color Atto 542, StreptaClick® Color 594, and StreptaClick® Color 647. Suitable for multiplex IHC. (Cat. no. 50041-1)
  • The StreptaClick® Color Complete kits also include our convenient BiotinPure™ Antibody Biotinylation kit in addition to the StreptaClick® Color reagents (2-plex Cat. no. 50022-1 , 4-plex Cat. no. 50042-1)
Order or request further information

Request a quote or order

Request a quote or order with payment by invoice by sending us an email via the button above. When ordering, please include information on the products you wish to order, organization, VAT number (only EU countries), delivery address, and invoice address. Please also state contact person and phone number for delivery by courier. We ship globally – a shipping cost of €50 is added to countries within the EU and €80 to all other countries. Upon request we can also charge in $USD for payments by invoice.

Webshop

Orders can also be placed through our webshop via the form below.  Once a product has been added a popup will appear with the choice of proceeding to checkout or adding additional products. The shopping cart icon at the top right corner also takes you to checkout. At checkout you will have the choice of secure payment by credit card via Stripe, Apple Pay, Google Pay or invoice. Shipping charges are added automatically. NB: VAT is not added to the final cost under Article 138 VAT directive (other EU countries) and 146 VAT directive (export to non-EU countries). Select your StreptaClick® Color Kit:
Select options This product has multiple variants. The options may be chosen on the product page