The StreptaClick® Technology
The patented StreptaClick® technology provides monovalent binding of streptavidin to biotinylated antibodies. StreptaClick® is a modified form of tetrameric streptavidin with conserved high binding affinity for biotin. Its monovalent binding properties also prevent antibody aggregation. StreptaClick® can be linked to any biotinylated antibody in a 5-minute mixing reaction, in any volume and without washing steps. Our product portfolio includes StreptaClick® labelled with fluorochromes, enzymes, and site-specifically attached single molecules (oligo, azide, alkyne).
SpectraSplit®7 – Hepta-band optical filter sets for microscopes
Specific separation of 7 fluorescent colors in a multi-stained tissue section has never been easier. The patented SpectraSplit®7 filter sets generate clean, sharp images without the need for spectral unmixing, making it suitable for any downstream application. Simply select among the most popular fluorochromes for each color channel and image without bleed-through.
SpectraSplit®7 was initially developed in 2014. Over the years the hepta-band filter sets have been fine-tuned based on customer feedback to not only fit a wide range of fluorochromes, but also different staining techniques, including Tyramide Signal Amplification and DNA-based multiplexing.
SpectraSplit®7 is compatible with light sources from CoolLED (pE-800 SB), Lumencor (SPECTRA X light engine) and Excelitas (NOVEM-S).
Introducing StreptaClick® Precision
A groundbreaking version of StreptaClick® developed for site-specific conjugation of a single molecule. StreptaClick® Precision has a unique design with maximum separation of the sites for conjugation and biotin binding. This makes StreptaClick® Precision ideal for attachment of oligonucleotides and other bulky molecules.
StreptaClick® Precision is provided with a single azide or alkyne group for standard click chemistry. It is also available pre-conjugated with a single 14 mer oligo or a single bright fluorochrome (488 and 647).
The combination of single molecule precision and flexibility makes StreptaClick® Precision the ultimate choice for attaching tetrameric streptavidin to biotinylated proteins without aggregation.
Perfectly Suited for oligos
BiotinPure™ Antibody Biotinylation Kit
SpectraSplit® 7
StreptaClick® Color
- The StreptaClick® 2-Color Kit contains: StreptaClick® Color 488 and StreptaClick® Color 647. Suitable for multiplex IHC and Flow Cytometry. (Cat no. 50021-1)
- The StreptaClick® 4-Color Kit contains: StreptaClick® Color 488, StreptaClick® Color 542, StreptaClick® Color 594, and StreptaClick® Color 647. Suitable for multiplex IHC. (Cat no. 50041-1)