The demand for multiplex immunostaining of tissues is rapidly increasing. However, multiplexing with more than 2-3 antibodies is challenging and often requires costly investments in new methods and instruments that entail time-consuming training for the users.
Our solution is simple and efficient. Multiplex with biotinylated antibodies and acquire 7-color images with unique filter sets compatible with any fluorescence microscope. Our technologies make multiplex IHC easy to perform without expert knowledge in histochemistry and spectral unmixing.
StreptaClick attaches reporter molecules with a rapid protein click reaction to biotinylated antibodies in solution. The technology is ideal for multiplex immunostaining with antibodies of the same animal species. Two products are currently available, StreptaClick–color and StreptaClick–HRP. The latter kit allows multiplex tyramide signal amplification (TSA) on frozen tissue sections, which has previously not been possible. More StreptaClick products are under development.
SpectraSplit is a unique combination of filter sets that specifically separate each fluorochrome in 7-color multiplex immunostainings without spectral unmixing. Just stain and acquire unmanipulated images of outstanding quality. SpectraSplit is optimized for the most commonly used fluorochromes used in multiplex IHC, such as Opal dyes, AlexaFluor dyes, and many more with similar spectra.
Kromnigon
c/o AstraZeneca R&D
Pepparedsleden 1
SE-43183 Mölndal
Sweden
info@kromnigon.com
Kromnigon
c/o AstraZeneca R&D
Pepparedsleden 3
SE-431 83 Mölndal
Sweden
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