Click Chemistry

StreptaClick® Precision — Monovalent Streptavidin for Click Chemistry

Customize StreptaClick® to fit your specific needs. We provide StreptaClick® equipped with a predetermined number of  alkyne groups (1-4), suitable for click chemistry. This allows you to attach 1, 2, 3, or 4 molecules with precision, catering to both small scale labeling and bulk production according to your application needs. You can attach your own biomolecules to these, allowing you to adapt StreptaClick® to your assays, target-seeking systems, or production enhancers. The controlled number of alkynes makes it easy for you to find the optimal StreptaClick® product for your needs. Additionally, StreptaClick® retains its biotin-binding capacity and can be easily linked to any biotinylated antibody or protein.

If you’re interested in exploring specific applications with StreptaClick®, please don’t hesitate to contact us.

Defined number of alkynes for Click Chemistry

Introducing StreptaClick® Precision, your ultimate tool for precise protein labeling. Our specially engineered monovalent streptavidin features customizable alkyne groups (ranging from 1 to 4) strategically attached, offering unparalleled control in your labeling process.

StreptaClick® Precision Workflow

Click Chemistry

Revolutionize your scientific endeavors with our cutting-edge range of click chemistry products. Engineered to streamline and amplify your research, our line offers versatile solutions tailored to meet diverse needs. From customizable StreptaClick® variants, equipped with precisely controlled alkyne groups for seamless molecule attachment, to a comprehensive selection of click-compatible reagents and tools, our products empower you to drive innovation in drug development, biomolecule labeling, and beyond. Experience efficiency and precision in every reaction, allowing you to unleash the full potential of click chemistry in your laboratory. Join the forefront of scientific advancement with our click chemistry solutions and transform your experiments into groundbreaking discoveries.

How it works

With StreptaClick® Precision, the labeling process becomes seamless. Connect the alkyne-labeled streptavidin to your biotinylated protein using just a single biotin link. Then, utilizing click chemistry—a powerful and precise method—attach your reporter molecule to your protein of interest through an alkyne/azide reaction. This method ensures accurate and specific labeling in every experiment.

This innovation grants you exquisite control over labeling positions and ratios, enabling detailed exploration of protein behaviors, interactions, and localization. Enhance sensitivity and specificity in your experiments, empowering your research to reach new heights.

Monovalent Streptavidin for Click Chemistry

Introducing StreptaClick® Precision, the cutting-edge solution revolutionizing biotechnology and molecular research. Engineered with unparalleled precision, this monovalent streptavidin redefines binding affinity to biotin, ensuring unmatched specificity in molecular interactions. What sets StreptaClick® Precision apart is its incorporation of 1 to 4 alkyne groups, perfectly primed for seamless integration with click chemistry.

From advanced bioconjugation techniques for high-resolution imaging in super-resolution microscopy to facilitating targeted drug delivery systems, StreptaClick® Precision’s versatility knows no bounds. Streamline protein purification processes, enhance protein detection assays, and empower oligonucleotide research with precise modifications and labeling. Its adaptability extends further, allowing the development of custom click chemistry-based assays for biomarker detection and molecular interaction studies.

With StreptaClick® Precision, delve into a realm of limitless applications, empowering scientists and researchers to explore, innovate, and elevate their discoveries to unprecedented heights across diverse scientific domains.

BiotinPure™ Antibody Biotinylation Kit

490 
The BiotinPure™ Antibody Biotinylation Kit is a complete kit for easy biotinylation of antibodies at room temperature within 1 hour. The kit uses amine/ester chemistry to attach 2-3 biotins per antibody and includes a purification wash step that removes unreacted free biotin from the final biotinylated antibody solution. The antibodies to be biotinylated should be free from other proteins, such as BSA. The BiotinPure™ Antibody Biotinylation Kit is designed for use with StreptaClick® reagents. The biotinylated antibodies may also be used for other applications. Cat. no. 9000051-1 Contact us for further information
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SpectraSplit® 7

SpectraSplit® 7 are patented filter sets that empower fluorescence microscopes with seven color channels.  The channels are distributed over four filter sets and specifically separate the most commonly used fluorochromes in immunofluorescence (see table below). Hence, you can immunostain tissues with up to seven fluorochromes and still visualize each fluorochrome in the sample with SpectraSplit® 7 without bleedthrough. No additional software and no computational spectral unmixing are required. SpectraSplit® 7 can easily be installed in both standard and scanning fluorescence microscopes, and can be run with different popular light sources. See the description below for more information. Cat no. 7001991-1 Request a Quote

StreptaClick® Color

570 935 
StreptaClick® Color labels antibodies with fluorochromes, mimicking directly conjugated antibodies. StreptaClick® Color provides a rapid, robust, and flexible method for attaching fluorochromes to biotinylated antibodies. Once labeled with StreptaClick®, the antibody is stable and can be used in the same manner as antibodies that are directly conjugated with fluorochromes. The click reaction is highly efficient and can be carried out at any volume, concentration, or buffer.
  • The StreptaClick® 2-Color Kit contains: StreptaClick® Color 488 and StreptaClick® Color 647. Suitable for multiplex IHC and Flow Cytometry. (Cat no. 50021-1)
  • The StreptaClick® 4-Color Kit contains: StreptaClick® Color 488, StreptaClick® Color 542, StreptaClick® Color 594, and StreptaClick® Color 647. Suitable for multiplex IHC. (Cat no. 50041-1)
Select your StreptaClick® Color Kit:
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StreptaClick® HRP

390 1690 
Introducing the StreptaClick® HRP Multiplex IHC Kit—your ultimate solution for efficient and high-quality multiplex TSA staining. This comprehensive kit is designed for researchers who demand precision and reliability in immunohistochemistry (IHC). The kit includes everything needed to label biotinylated antibodies with horseradish peroxidase (HRP), featuring a novel HRP block buffer that eliminates the need for boiling between cycles, making it ideal for both frozen and FFPE tissue sections.
Select your StreptaClick® HRP Kit:
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StreptaClick® Precision

390 3600 
StreptaClick® Precision is developed for site-specific conjugation with a defined number of attachment groups. Furthermore, StreptaClick® Precision has a unique design with maximum separation of the sites for conjugation and biotin binding. This design makes StreptaClick® Precision ideal for attachment of oligonucleotides and other bulky molecules without affecting the biotin binding quality and without causing aggregation when mixed with biotinylated proteins. StreptaClick® Precision is currently provided with a single azide or alkyne group for standard click chemistry. It is also available pre-conjugated with a single 14 mer oligo or a single bright fluorochrome (488 and 647). Contact us for further information
Select options This product has multiple variants. The options may be chosen on the product page